COREDesignerAPI

Product

onepot Designer

The synthesis data-aware molecule design environment. Sketch a query structure, set property constraints, and explore make-on-demand neighbors anchored on what our lab can actually make.

BTK inhibitor analogs

Structure

Pick one or more

Property filters

No min20050010001000
No min-2.00.02.05.08.0
No min5101520
No min351015
No min246No max
No min6090140250
Filter
Tanimoto ≥0%
Sort
Structure + Fragment · 7 compounds · MW ≤ 500
4424.11D4A
4263.41D6A
4253.91D5A
4694.21D4A
4244.01D4A
4414.31D4A
4103.61D5A

Anchored generation

Designer generates analogs that stay close to your query — by structure or by fragment — and ranks them by predicted feasibility against the onepot CORE compound space.

Property-aware sliders

Constrain MW, LogP, HBA/HBD, aromatic rings, and TPSA. The Designer keeps proposals inside the box while preserving the chemistry that matters.

Routes you can order

Every proposed molecule comes with a forward route from commercially available building blocks. One click sends it to a quote.

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Designer is a UI on top of our first generative model, trained on closed-loop synthesis data from our automated lab.

Open Designer