Introducing onepot Flow

When we launched onepot, the core promise was straightforward: you tell us what molecules you need, and we make them. The search and synthesis infrastructure was there from the start. What was missing was a structured way to go from “I found interesting compounds” to “here is my order, with the terms I want.”

Today we are launching the onepot Flow — a secure end-to-end workflow that takes compound selection, route-level pricing, order configuration, and submission and puts it all in one place.

How onepot Flow works

The system lets you build a quote by importing molecules from CSV, Excel, or CDXML files, or by drawing structures directly in the browser. Once your compounds are in, we evaluate synthesis routes in real time and return per-route pricing with risk annotations for each option. You pick the route that fits your timeline and budget, configure your delivery preferences, and place the order — all without leaving the platform.

Why this does not exist yet

Custom synthesis ordering in 2026 still runs via email. You send a list of SMILES to a vendor, wait days for a PDF with quotation, negotiate terms over a chain of replies, and hope the pricing still holds by the time you get budget approval. There is no platform in the market where you can go from a molecule to a priced, configured order in a single session. The reason is simple: real-time pricing requires tight coupling between route prediction, inventory state, and feasibility models: things most vendors do not have in software. We do, and the quoting system is the interface that exposes it.

Each compound can have multiple synthesis routes, and each route carries its own supplier risk, chemistry risk, estimated timeline, and price. This means you are not locked into a single option per molecule. If one route is cheaper but slower, and another is faster but carries a higher chemistry risk, you can see both and decide. onepot Flow is designed to help you make the right choice.

Configurable order terms

Synthesis does not always go as planned. Yields can be low, purity can fall short, and sometimes a reaction produces multiple isomers. The quoting system lets you set policies for all of these cases upfront. You choose what happens when we obtain less than 0.5 mg, what discount schedule applies for low-purity compounds, whether to ship all isomers or only the major product, and when to consider an order complete. These are not hypothetical settings: they map directly to decisions that come up in every synthesis campaign, and getting them right before work starts will avoid back-and-forth later.

What this changes

The quoting system closes the loop between compound discovery and compound ordering. The entire path from search to order now lives inside onepot, with real-time pricing driven by the same synthesis models that power our lab. No emails, no PDFs, no waiting.

Route pricing is not a static lookup — it reflects the current state of our building block inventory, the feasibility scores from our reaction models, and the expected load on our synthesis platform. As our models improve, pricing gets more accurate automatically.

What is next

This is the first version. We plan to add analog suggestions when an exact molecule is not in our compound space, bulk route comparison across entire quote libraries, and tighter feedback loops where synthesis outcomes improve pricing models. The goal is the same as everything else we build: remove the friction between wanting a molecule and having it in your hands.

If you want to try onepot Flow or have feedback on how it should work for your use case, reach out to hello@onepot.ai .