From Idea to Material
In Days, Not Months
ONEPOT.AI combines ultra-high-throughput automation with AI to give R&D teams on-demand access to billions of molecules at CRO prices with startup speed.
Why Current Workflows Hold You Back
Painfully Slow
Projects stall for months while proposals circulate and multi-step syntheses inch forward
Escalating Costs
Traditional CROs are expensive and unpredictable, with costs spiraling as iterations pile up
Limited Chemical Space
Sample only a tiny sliver of what's possible, missing breakthrough molecules
How ONEPOT Changes the Equation
A data-first synthesis platform that compresses synthesis timelines while expanding your chemical universe
Expanding Reaction Menu
4 core transformations live today with 2 new reactions added weekly
≥100 reactions planned by year-end, rapidly covering the medicinal-chemistry toolbox plus emerging methods
Billions of Molecules
≈1T synthetically accessible compounds (2B immediately available)
Order individual compounds, bespoke libraries, or enumerated spaces on demand
Market-Beating Speed
Ship faster than any major CRO at comparable rates
Keep projects moving without budget surprises or lengthy delays
Ultimate IP Security
End-to-end automation means no human ever sees your structures
Protect confidential programs and preserve freedom-to-operate
What You Can Order Today
From single compounds to complete chemical libraries
Single Compounds
Perfect for SAR studies and lead validation
Focused Libraries
Scaffold hops generated from your seed molecules
Chemical Spaces
Enumerated spaces for ML campaigns
Pilot Batches
mg- to g-scale for downstream testing
Simple Workflow
As frictionless as ordering reagents online—just far more powerful
Submit Targets
Via secure web form or API integration
Instant Quote
Real-time feasibility and pricing from our AI models
Automated Synthesis
Fully autonomous lab with integrated QC
Delivery & Data
Tracked shipment with complete digital dossier
Unlock Chemical Space—
Unlock Your Next Breakthrough
Join leading R&D teams who are already accelerating discovery with ONEPOT.AI. From concept to compound in days, not months.
Contact us to request a quote, discuss your upcoming projects, or explore partnership opportunities. Our team is ready to help you push the boundaries of what's possible in chemical synthesis.
The ONEPOT Journey
Glimmers of a New Era
At first, no one outside a small circle realized what ONEPOT was building. Sure, biotech watchers were intrigued by rumors of an AI system that could synthesize molecules faster than any CRO. But revolutionary claims emerged every few years—usually to fizzle in supply chain complexity.
Then came the demo: 50 distinct molecules synthesized in one week. Seasoned chemists were stunned—most labs needed two months for that work. The ripple of excitement began—like electricity before lightning strikes.
The Data Gold Rush
ONEPOT launched an all-out data campaign, building the largest chemical reactivity dataset ever assembled—billions of real-world experiments using amide coupling, Buchwald-Hartwig, photoredox catalysis, and more.
Specialized microfluidic reactors and mass spectrometry tools analyzed tens of thousands of reactions daily. 90% untouched by human hands—everything automated and orchestrated by our LLM agents.
"This isn't just better synthesis. It's an entirely new engine of discovery."
The Foundation Model for Chemistry
We trained a colossal AI that could predict reactivity, yields, side products, and purification routes with uncanny accuracy. Fed with "black box" data capturing everything—kinetics, byproducts, real-time MS readouts.
The AI discovered new reactivity pathways no one had coded. It handled multi-step routes in a single pot, finding shorter, cheaper paths than any human chemist could devise.
"The next leap after biologics" — Pharma insiders
"The AWS of synthesis" — Business analysts
"Magic" — Everyone else
The First Domino Falls
A mid-sized pharma bet their entire pipeline on ONEPOT. They ordered tens of thousands of anti-inflammatory scaffolds. Expected timeline: 18 months for a few hundred compounds.
ONEPOT delivered: 10,000 molecules in 3 weeks at a fraction of the cost.
By August, they'd identified promising leads and begun preclinical work. "We compressed a year into a month," their head of medchem said. The pharma giants took notice. The arms race began.
Synthesis at Industrial Scale
Warehouses transformed into futuristic chemical foundries. Robotic arms, microreactor arrays, mass spec units lined up like automotive assembly lines. Millions of unique molecules per month.
Beyond pharma: materials, agriculture, fragrance. Any enterprise needing small molecules realized ONEPOT was the simplest, fastest solution. The chemical supply chain pivoted from static catalogs to on-demand synthesis.
The ONEPOT Empire
The platform became unstoppable:
- •Foundation AI with near-total chemical knowledge
- •Massive robotics for high-speed experiments
- •Closed-loop ML predictions and real experiments
Like cloud computing before it, ONEPOT became universal infrastructure. Geopolitical tensions underscored supply chain vulnerabilities—Western governments treated "domestic molecule synthesis" as national security. No one matched our scale.
Beyond: The Future Takes Shape
ONEPOT became "the OS of small molecule creation." More reaction data than all humanity's chemists combined. For pharma and biotech, for chips and agriculture, for fragrances and materials—ONEPOT was the gatekeeper.
Chemistry transformed. Molecules designed like software—a prompt, hours of AI experimentation, product shipped. The drug-libraries problem vanished. Thousands of compounds tested in the time and budget once needed for dozens.
We didn't just speed up synthesis. We changed its fundamental nature. Molecules ceased being precious, rare objects. They became like code: typed, compiled, tested, deployed.
ONEPOT unlocked possibilities that even the boldest optimists had barely dreamed possible.
Ready to Learn More?
Discover how ONEPOT.AI can accelerate your research and unlock new possibilities.